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SCIENTIFIC SCORE
Possibly Effective
Based on 45 Researches
7.2
USERS' SCORE
Good
Based on 20 Reviews
8.6
Supplement Facts
Serving Size: 3 Soft Gels
Amount Per Serving
%DV
Calories
35
Total Fat
3 g
4%
Saturated Fat
0.5 g
3%
Trans Fat
0 g
†
Cholesterol
15 mg
5%
Vitamin A
30 mcg RAE
3%
Total Omega-3s
750 mg
†
EPA (Eicosapentaenoic Acid)
240 mg
†
DHA (Docosahexaenoic Acid)
360 mg
†
Other Omega-3s
150 mg
†
Top Medical Research Studies
9
Eicosapentaenoic acid benefits cholesterol
Omega-3 eicosapentaenoic polar-lipid rich extract from microalgae decreases plasma triglycerides and cholesterol in a real-world normolipidemic supplement consumer population.
Direct focus on EPA's efficacy
We explored the effects of eicosapentaenoic acid (EPA), a specific type of omega-3 fatty acid, on cholesterol levels in a recent study involving real-world supplement consumers. Participants took AlmegaPL capsules, which contain high amounts of EPA and are free of the other omega-3 fatty acid, DHA. This setup allowed us to gain insights from those who are already incorporating EPA into their diets.
Throughout the study, we monitored key health markers such as triglycerides, total cholesterol, and various types of cholesterol at different stages of supplementation. We observed that after six months of taking this supplement, participants showed a significant reduction in remnant cholesterol and maintained healthy triglyceride levels. Notably, this decrease in cholesterol did not come at the expense of raising low-density lipoprotein (LDL) levels, which is often a concern with other treatments.
These encouraging results reveal that EPA can be a beneficial addition for individuals looking to manage their cholesterol levels effectively. Importantly, our findings highlight AlmegaPL's unique position as a natural, over-the-counter option for those seeking to improve their lipid profiles.
Throughout the study, we monitored key health markers such as triglycerides, total cholesterol, and various types of cholesterol at different stages of supplementation. We observed that after six months of taking this supplement, participants showed a significant reduction in remnant cholesterol and maintained healthy triglyceride levels. Notably, this decrease in cholesterol did not come at the expense of raising low-density lipoprotein (LDL) levels, which is often a concern with other treatments.
These encouraging results reveal that EPA can be a beneficial addition for individuals looking to manage their cholesterol levels effectively. Importantly, our findings highlight AlmegaPL's unique position as a natural, over-the-counter option for those seeking to improve their lipid profiles.
Read More
9
DHA lowers cholesterol; boosts metabolism
F-Fluorodeoxyglucose positron emission tomography/computed tomography imaging reveals the protective effect of docosahexaenoic acid on glucose metabolism by reducing brain 27-hydroxycholesterol.
Directly addresses cholesterol effects
We aimed to investigate how docosahexaenoic acid (DHA) impacts cholesterol levels and brain glucose metabolism. In our study, we focused on aged SAMP8 mice, dividing them into two groups: a control group and one receiving DHA supplementation.
Our results revealed encouraging changes; the group that received DHA showed a decrease in total cholesterol and low-density lipoprotein cholesterol, while high-density lipoprotein cholesterol levels increased. More importantly, we observed improvements in glucose metabolism in various brain regions, including the cortex and hippocampus.
These findings suggest that DHA may help lower harmful cholesterol levels and enhance brain function by regulating specific cholesterol compounds like 27-hydroxycholesterol, which are linked to glucose metabolism. Overall, our study highlights DHA's potential in supporting heart and brain health through cholesterol management.
Our results revealed encouraging changes; the group that received DHA showed a decrease in total cholesterol and low-density lipoprotein cholesterol, while high-density lipoprotein cholesterol levels increased. More importantly, we observed improvements in glucose metabolism in various brain regions, including the cortex and hippocampus.
These findings suggest that DHA may help lower harmful cholesterol levels and enhance brain function by regulating specific cholesterol compounds like 27-hydroxycholesterol, which are linked to glucose metabolism. Overall, our study highlights DHA's potential in supporting heart and brain health through cholesterol management.
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7
Cod liver oil affects cholesterol differently
Effects of cod liver oil on lipids and platelets in males and females.
Directly addresses cholesterol treatment
We observed the effects of cod liver oil (CLO) on cholesterol levels and platelet function in a controlled study involving 34 healthy adults, including both men and women. Participants took 25 ml of CLO daily for eight weeks, allowing us to measure changes in their lipid profiles and platelet responsiveness before and after the intervention.
Before taking CLO, women had notably higher total and HDL (good) cholesterol levels compared to men, as well as higher platelet counts. Interestingly, women showed a lower response to collagen stimulation in their platelets, indicating different baseline platelet activity. After the CLO treatment, we found that men's serum triglyceride levels decreased, while their LDL (bad) cholesterol increased. This rise in LDL was statistically significant when compared to women, who did not exhibit any notable change in LDL levels.
It's important to note that while the mean platelet volume increased for both sexes, men experienced a reduced sensitivity to collagen after taking CLO, which was a significant finding as this effect did not occur in women. Overall, the study suggests notable sex differences in how cod liver oil impacts cholesterol levels and platelet responses, emphasizing the need for gender-specific assessments in dietary supplements.
Before taking CLO, women had notably higher total and HDL (good) cholesterol levels compared to men, as well as higher platelet counts. Interestingly, women showed a lower response to collagen stimulation in their platelets, indicating different baseline platelet activity. After the CLO treatment, we found that men's serum triglyceride levels decreased, while their LDL (bad) cholesterol increased. This rise in LDL was statistically significant when compared to women, who did not exhibit any notable change in LDL levels.
It's important to note that while the mean platelet volume increased for both sexes, men experienced a reduced sensitivity to collagen after taking CLO, which was a significant finding as this effect did not occur in women. Overall, the study suggests notable sex differences in how cod liver oil impacts cholesterol levels and platelet responses, emphasizing the need for gender-specific assessments in dietary supplements.
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Most Useful Reviews
8.8
Improved cholesterol levels
I appreciate that this is a quality supplement with just one ingredient, making it safe for my child who has been using it since aged 4. It has no fishy taste, is beneficial for heart health, and helps manage high cholesterol and inflammation. My skin is also more hydrated since taking it.
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8.8
Cholesterol management
There’s no fish taste and the soft gel tablets are easy to swallow. This product has helped manage my high cholesterol, supports heart health, and improves my asthma. I have noticed thicker hair too. I take 2-3 soft gels daily after breakfast.
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9.5
Excellent omega balance
This high-quality cod liver oil has no fishy smell. I chose it for its balance of omega 3 fatty acids and vitamins A and D, which are crucial for heart health and managing high cholesterol. I prefer the lemon-flavoured liquid over capsules.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 45 Researches
7.2
9
Eicosapentaenoic acid aids cholesterol
Antarctic Krill Oil Supplementation Attenuates Hypercholesterolemia, Fatty Liver, and Oxidative Stress in Diet-Induced Obese Mice.
Study shows EPA's combined effects
We explored the effects of eicosapentaenoic acid (EPA) from Antarctic krill oil (ESKO) on cholesterol levels and obesity-related conditions. Through a carefully designed study involving mice on a high-fat diet, we wanted to see if ESKO could improve cholesterol metabolism and reduce fat accumulation.
We found that diets high in fat significantly increased oxidative stress and indicators associated with obesity. However, supplementation with ESKO appeared to counteract these negative effects, helping to reduce fat buildup and improve cholesterol levels.
Specifically, ESKO improved important metabolic pathways and reduced the activity of certain proteins that typically promote high cholesterol. This suggests that eicosapentaenoic acid from krill oil could play a crucial role in tackling high cholesterol and obesity-related disorders.
We found that diets high in fat significantly increased oxidative stress and indicators associated with obesity. However, supplementation with ESKO appeared to counteract these negative effects, helping to reduce fat buildup and improve cholesterol levels.
Specifically, ESKO improved important metabolic pathways and reduced the activity of certain proteins that typically promote high cholesterol. This suggests that eicosapentaenoic acid from krill oil could play a crucial role in tackling high cholesterol and obesity-related disorders.
Read More
9
Eicosapentaenoic acid reduces cholesterol inflammation
EPA and DHA inhibit LDL-induced upregulation of human adipose tissue NLRP3 inflammasome/IL-1β pathway and its association with diabetes risk factors.
Relevant support for cholesterol management
We explored how eicosapentaenoic acid (EPA) affects cholesterol levels and the risk of type 2 diabetes (T2D). Our study focused on individuals with high levels of atherogenic lipoproteins, specifically apoB, which are known to predict higher diabetes risk. Over a twelve-week period, participants received daily doses of EPA and docosahexaenoic acid (DHA) to see how these omega-3 fatty acids influenced the secretion of interleukin-1 beta (IL-1β) from human white adipose tissue (WAT).
Remarkably, our results showed that EPA and DHA treatment effectively normalized the IL-1β secretion levels in participants who initially had high apoB. After the intervention, LDL cholesterol no longer triggered IL-1β secretion, and the omega-3 supplementation also improved overall β-cell function and fat metabolism. This means that not only did EPA and DHA reduce inflammation linked to high cholesterol, but they also appeared to enhance metabolic health.
Additionally, we found that the supplementation reduced the association between WAT inflammasome activity and various cardiometabolic risk factors, such as increased body fat. In laboratory tests, EPA and DHA inhibited WAT IL-1β secretion in a dose-dependent manner. These findings suggest that incorporating EPA and DHA into our diets may help prevent diabetes and its related health issues in individuals with high apoB levels.
Remarkably, our results showed that EPA and DHA treatment effectively normalized the IL-1β secretion levels in participants who initially had high apoB. After the intervention, LDL cholesterol no longer triggered IL-1β secretion, and the omega-3 supplementation also improved overall β-cell function and fat metabolism. This means that not only did EPA and DHA reduce inflammation linked to high cholesterol, but they also appeared to enhance metabolic health.
Additionally, we found that the supplementation reduced the association between WAT inflammasome activity and various cardiometabolic risk factors, such as increased body fat. In laboratory tests, EPA and DHA inhibited WAT IL-1β secretion in a dose-dependent manner. These findings suggest that incorporating EPA and DHA into our diets may help prevent diabetes and its related health issues in individuals with high apoB levels.
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9
High-purity EPA benefits cholesterol
Pleiotropic beneficial cardiometabolic actions of a high-purity eicosapentaenoic acid product in high cardiovascular risk individuals.
Pleiotropic benefits for heart health
We examined the impact of a highly purified eicosapentaenoic acid (EPA) formulation on cholesterol levels and overall heart health in individuals considered at high risk for cardiovascular issues. The study involved 226 patients who had high triglycerides and one or more cardiovascular risk factors, such as hypertension or diabetes.
Participants received 4 grams of EPA daily for three months alongside regular nutritional counseling. By tracking key health markers, we noted significant improvements in cholesterol levels, particularly in triglycerides and low-density lipoprotein (LDL). For instance, triglyceride levels dropped from an average of 2.97 mmol/L to 1.75 mmol/L in just three months.
Additionally, we found improvements in other important metrics, including total cholesterol and glucose levels, indicating that EPA supplementation may have broad benefits for cardiometabolic health. Although apolipoprotein A levels did not change significantly, the overall trend suggests that incorporating EPA could play a role in achieving better heart health outcomes.
Participants received 4 grams of EPA daily for three months alongside regular nutritional counseling. By tracking key health markers, we noted significant improvements in cholesterol levels, particularly in triglycerides and low-density lipoprotein (LDL). For instance, triglyceride levels dropped from an average of 2.97 mmol/L to 1.75 mmol/L in just three months.
Additionally, we found improvements in other important metrics, including total cholesterol and glucose levels, indicating that EPA supplementation may have broad benefits for cardiometabolic health. Although apolipoprotein A levels did not change significantly, the overall trend suggests that incorporating EPA could play a role in achieving better heart health outcomes.
Read More
9
Eicosapentaenoic acid benefits cholesterol
Omega-3 eicosapentaenoic polar-lipid rich extract from microalgae decreases plasma triglycerides and cholesterol in a real-world normolipidemic supplement consumer population.
Direct focus on EPA's efficacy
We explored the effects of eicosapentaenoic acid (EPA), a specific type of omega-3 fatty acid, on cholesterol levels in a recent study involving real-world supplement consumers. Participants took AlmegaPL capsules, which contain high amounts of EPA and are free of the other omega-3 fatty acid, DHA. This setup allowed us to gain insights from those who are already incorporating EPA into their diets.
Throughout the study, we monitored key health markers such as triglycerides, total cholesterol, and various types of cholesterol at different stages of supplementation. We observed that after six months of taking this supplement, participants showed a significant reduction in remnant cholesterol and maintained healthy triglyceride levels. Notably, this decrease in cholesterol did not come at the expense of raising low-density lipoprotein (LDL) levels, which is often a concern with other treatments.
These encouraging results reveal that EPA can be a beneficial addition for individuals looking to manage their cholesterol levels effectively. Importantly, our findings highlight AlmegaPL's unique position as a natural, over-the-counter option for those seeking to improve their lipid profiles.
Throughout the study, we monitored key health markers such as triglycerides, total cholesterol, and various types of cholesterol at different stages of supplementation. We observed that after six months of taking this supplement, participants showed a significant reduction in remnant cholesterol and maintained healthy triglyceride levels. Notably, this decrease in cholesterol did not come at the expense of raising low-density lipoprotein (LDL) levels, which is often a concern with other treatments.
These encouraging results reveal that EPA can be a beneficial addition for individuals looking to manage their cholesterol levels effectively. Importantly, our findings highlight AlmegaPL's unique position as a natural, over-the-counter option for those seeking to improve their lipid profiles.
Read More
9
Krill oil supports cholesterol management
Antarctic Krill Oil Supplementation Attenuates Hypercholesterolemia, Fatty Liver, and Oxidative Stress in Diet-Induced Obese Mice.
Moderate relevance for DHA impact
We explored how Antarctic krill oil, particularly its key components like docosahexaenoic acid (DHA), can combat high cholesterol and obesity-related issues. Our study focused on its effects in a controlled environment using obese mice that were fed a high-fat diet.
We observed that when these mice were supplemented with krill oil, there were notable reductions in cholesterol levels and fat accumulation. It seemed to positively influence various metabolic pathways, such as those associated with cholesterol metabolism.
Specifically, DHA, along with other nutrients found in krill oil, appears to aid in lowering oxidative stress and improving cholesterol metabolism. While the benefits of DHA alone weren't isolated in this study, the overall findings suggest that krill oil may work effectively in reducing the risks tied to obesity and high cholesterol.
Overall, this research indicates that incorporating krill oil into our diets could be a promising strategy for managing cholesterol levels and supporting heart health.
We observed that when these mice were supplemented with krill oil, there were notable reductions in cholesterol levels and fat accumulation. It seemed to positively influence various metabolic pathways, such as those associated with cholesterol metabolism.
Specifically, DHA, along with other nutrients found in krill oil, appears to aid in lowering oxidative stress and improving cholesterol metabolism. While the benefits of DHA alone weren't isolated in this study, the overall findings suggest that krill oil may work effectively in reducing the risks tied to obesity and high cholesterol.
Overall, this research indicates that incorporating krill oil into our diets could be a promising strategy for managing cholesterol levels and supporting heart health.
Read More
User Reviews
USERS' SCORE
Good
Based on 20 Reviews
8.6
9.5
Excellent omega balance
This high-quality cod liver oil has no fishy smell. I chose it for its balance of omega 3 fatty acids and vitamins A and D, which are crucial for heart health and managing high cholesterol. I prefer the lemon-flavoured liquid over capsules.
9.5
Elderly suitability
I bought cod liver oil for my mother to help manage her high cholesterol. After three months, her levels normalised, and it also reduced inflammation. The taste is acceptable, and it is suitable for older adults.
9.5
Beneficial for cholesterol
The best omega supplement is excellent and indispensable, with high-quality ingredients. This is my third purchase. It is beneficial for my heart, reduces inflammation, and lowers high cholesterol. Its taste is acceptable, and it also benefits my eyes and hair. Quality is guaranteed.
9.5
Fights cholesterol inflammation
Excellent Cod Liver Oil! Nordic Naturals offers high-quality cod liver oils with concentrated EPA and DHA, fighting inflammation and lowering high cholesterol levels. It is also beneficial for heart health and tastes very good. I highly recommend it and will buy again.
9.5
Improves high cholesterol
Awesome! The quality is excellent, with good ingredients that do not cause body odour or aftertaste. It noticeably improves hair, nails, skin, and mood. For those with high cholesterol, it boosts memory and concentration, strengthens eyesight, and enhances heart health. I recommend using it continuously for the best results.
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